TULSA, Okla. (AP) - Sterling Gibbs (Scotch Plains, N.J.) scored 20 points and Shonn Miller (Euclid, Ohio) contributed 14 points and eight rebounds for UConn (11-5, 2-2), which dropped its first road game of the year.
The Huskies led by 11 in the first half and by as much as eight early in the second, but Tulsa battled back, using a 19-4 run over a span of 7:30 to take over the game.
James Woodard scored 20 points and added nine rebounds to lead Tulsa.
After the teams entered halftime tied 26-26, UConn came out strong following the break, scoring the first seven points and using a 10-2 run to go ahead 36-28 after Gibbs' 3-pointer with 3:51 elapsed in the second half.
Over the first seven and a half minutes of the second half, Tulsa shot just 1-for-10 from the floor, but after Brandon Swannegan's layup with 12:11 remaining, trailed just 37-34.
UConn jumped out to a fast start, building up a quick 8-0 lead over the first 2:30 of play, six of the points coming on back-to-back 3-pointers from Miller. Tulsa responded with a 7-0 run, pulling to within one after Harrison's steal, fast break and layup with 4:23 gone in the first half.
The Huskies then answered with a 10-0 run, going up 18-7 after Hamilton's 3-pointer with 12:12 left in the opening half.
Tulsa continued to battle back, as Rashad Smith's free throw with 3:10 remaining in the half capped an 11-0 run to make it 23-21, sending the home crowd into a frenzy.
Connecticut: Junior guard Rodney Purvis, who entered the game as UConn's top scorer averaging 15.1 points per game, scored just five points on 1-for-9 shooting, marking his first game of the season in single digits. Purvis had scored 10 or more in all previous 15 contests this season and in 21 consecutive, dating back to last season.
Tulsa: Senior guard Shaquille Harrison entered the day ranking 10th in the nation in free throw attempts, with an average of 8.1 per game, but shot just four times from the line, making three.
Connecticut finishes up a two-game road trip on Sunday at Houston.
Tulsa travels to face East Carolina next Tuesday.